Longevity Science for Men Who Play the Long Game
You’re Not Just Getting Older. You’re Getting Slower at Recovering From It.
The difference between men who age well and men who don’t isn’t luck—it’s biology. And biology is something you can work with. TRTPower’s Longevity protocols target the cellular mechanisms behind aging: energy production, inflammation, insulin resistance, and oxidative stress. This is preventive medicine for men who want to be sharp, strong, and capable at 65 the way they were at 45.
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Science-Backed, Doctor-Prescribed
Not supplements. Real prescriptions from licensed physicians who specialize in longevity and performance medicine.
Four Targeted Protocols
Each treatment targets a different cellular mechanism behind aging. Use them individually or let your doctor build the combination that fits your biology and your goals.
Delivered to Your Door
Discreet home delivery with everything included. Professional guidance and ongoing monitoring from start to finish.
You’re Not Ready to Slow Down. Science Says You Don’t Have To.
You’re not here because something is catastrophically wrong. You’re here because you’re paying attention—and what you’re noticing is that recovery takes longer than it used to. That mental sharpness feels harder to maintain. That the body composition you maintained effortlessly at 38 requires twice the work at 48. That low-grade inflammation, stiff joints, and inconsistent energy are becoming a pattern you’re not willing to accept as normal.
The men who age best aren’t doing it by accident. They’re doing it by addressing the underlying biology—the cellular energy systems, the metabolic regulators, the oxidative stress that compounds quietly until it isn’t quiet anymore.
TRTPower’s Longevity protocols are for men who want to be the 60-year-old in the room who moves better, thinks sharper, and recovers faster than men ten years younger. The ones who are still fully present for the people who need them—not managing a slow decline.
THE FOUR PROTOCOLS
Each protocol targets a different mechanism of biological aging. Use one or stack them—your doctor will help you build the right combination based on your goals, health history, and labs.
NAD+ — Cellular Energy & Biological Age
$199/month
NAD+ (Nicotinamide Adenine Dinucleotide) is one of the most critical molecules in your body—and after 40, your levels drop by roughly half. NAD+ is what your cells use to produce energy, repair DNA, and regulate the proteins that control how you age at a cellular level. When NAD+ declines, everything downstream suffers: energy production slows, cellular repair becomes less efficient, and the biological clock accelerates.
Injectable or Nasal NAD+ restores what aging takes away—with significantly better absorption than oral precursors that rely on a conversion chain your aging cells may not be completing efficiently.
What men experience with NAD+:
• Noticeably improved energy, often within days of starting
• Sharper cognitive function and mental clarity
• Reduced inflammation and improved recovery from training
• Better sleep quality and more consistent daily energy
• Cellular repair mechanisms operating at a higher level
How it’s taken: Subcutaneous injection or nasal spray administered at home. Our care team walks you through the process—straightforward, minimal discomfort, and completed in under a minute.
Rapamycin — Cellular Renewal & Aging Pathways
$149/month
Rapamycin is one of the most studied compounds in longevity research—and one of the most compelling. It works by inhibiting mTOR (mechanistic target of rapamycin), a cellular signaling pathway that, when chronically overactive, accelerates aging at the biological level. Intermittent low-dose Rapamycin—the protocol used in clinical longevity settings—has been shown to improve immune function, reduce markers of cellular aging, and extend healthy lifespan in research settings more consistently than almost any other compound studied.
This is not a supplement. It is a prescription medication with a serious research basis, used off-label in longevity medicine by physicians who specialize in this field. Your doctor will determine whether you are an appropriate candidate and will monitor you closely throughout treatment.
What men experience with Rapamycin:
• Improved cellular autophagy (the process by which cells clear out damaged components)
• Enhanced immune function, particularly relevant for men over 50
• Reduction in chronic inflammation markers
• Support for cognitive health and neuroprotection
• Potential reduction in biological aging rate over time
How it’s taken: Low-dose oral medication taken once weekly—the intermittent protocol used in clinical longevity practice. Your doctor will calibrate the dose based on your health profile.
Note: Rapamycin is a prescription medication with specific candidacy criteria. A thorough medical evaluation and regular monitoring are required. Your doctor will be direct about whether this protocol is appropriate for you.
Glutathione — Oxidative Defense & Cellular Protection
$175/month
Glutathione is your body’s primary antioxidant—the molecule your cells use to neutralize the oxidative stress that accumulates from training, environmental toxins, chronic stress, and simply living. When glutathione is depleted, oxidative damage compounds. Inflammation increases. Recovery slows. Cognitive function dulls. And the biological aging process accelerates.
The problem is that oral glutathione is poorly absorbed—most of it is broken down before it reaches your cells. Injectable glutathione bypasses this limitation entirely, delivering maximum absorption directly into your bloodstream where it can do what your cells actually need it to do.
What men experience with Glutathione:
• Faster recovery from training and physical stress
• Reduced inflammatory markers and joint discomfort
• Improved skin clarity and visible reduction in oxidative aging
• Sharper cognitive function and reduced brain fog
• Strengthened immune response and reduced illness frequency
• Enhanced liver function and detoxification
How it’s taken: Intramuscular or subcutaneous injection administered at home. Typically weekly. Our care team provides full guidance—straightforward and quick once you’ve done it once.
Metformin — Metabolic Health & Longevity Signaling
$79/month
Metformin has been prescribed for metabolic health for decades—and the longevity research community has spent the last ten years paying very close attention to it for a different reason. Beyond its effects on blood sugar regulation, Metformin activates AMPK, a cellular pathway that essentially signals your body to operate in a more efficient, stress-resistant mode. It has been shown to reduce inflammatory markers, lower the risk of age-related disease, and extend healthy lifespan in multiple research models.
For men with insulin resistance (more common than most realize, even without a formal diabetes diagnosis), metabolic dysfunction, or a family history of age-related disease, Metformin represents one of the most evidence-backed longevity interventions available.
What men experience with Metformin:
• Improved insulin sensitivity and metabolic regulation
• Reduction in chronic low-grade inflammation
• Support for healthy weight and body composition
• Better long-term cardiovascular risk profile
• Activation of cellular longevity pathways (AMPK/mTOR)
How it’s taken: Oral medication taken daily with food. Simple—no injections, no complicated protocols.
Note: Metformin is most appropriate for men with metabolic risk factors or elevated blood sugar markers. Your doctor will review your labs to determine if you’re a clinical candidate.
BUILD YOUR STACK
Start with your biggest gap. Build from there.
Most men begin with the protocol that targets their most pressing concern—then layer in additional protocols as they see results and dial in their approach. Your doctor will help you sequence it intelligently.
The Full Longevity Stack — All Four Protocols
For men who want comprehensive protection across every cellular system. Energy production, metabolic regulation, cellular renewal, and oxidative defense all addressed at once. This is the systematic approach for men who are serious about how they age.
Metformin + Rapamycin — The Longevity Pathway Stack
For men focused on biological age and long-term disease prevention. The most research-backed combination for activating cellular longevity pathways, reducing chronic inflammation, and targeting the metabolic and mTOR signaling that determines how fast you age. Candidacy evaluation required.
NAD+ + Glutathione — The Cellular Defense Stack
For men focused on recovery, inflammation, and cellular energy. NAD+ restores the energy your cells need to repair; Glutathione neutralizes the oxidative stress that accelerates aging. Together they cover the two most immediate cellular mechanisms of decline.
NAD+ + Metformin — The Metabolic Performance Stack
For men dealing with low energy, brain fog, and metabolic resistance. NAD+ addresses cellular energy production at the source; Metformin corrects the insulin resistance and metabolic dysfunction that drain it. A powerful combination for men whose performance decline has a metabolic component.
THE FOUNDATION
Longevity Isn’t a Single Switch. It’s a System.
TRT gives you hormonal optimization. Peak Performance protocols drive physical output and cognitive edge. Longevity protocols address the layer beneath all of it—the cellular systems that determine how efficiently your body ages, recovers, and sustains performance over time.
These protocols are designed to work alongside TRT and Peak Performance therapies, not instead of them. NAD+ pairs naturally with Sermorelin and B12—all three support recovery and energy at different levels of the biology. Metformin’s anti-inflammatory effects complement the hormonal balance TRT provides. Rapamycin addresses cellular aging mechanisms that no other protocol touches.
If you’re not on TRT and your testosterone levels are healthy, Longevity protocols stand completely on their own. The biology of cellular aging doesn’t require a hormone deficiency as a starting point. High-performing men with healthy hormone levels age too—and these protocols are designed for exactly that situation.
HOW IT WORKS
Simple Process, Real Support
Talk to Us First (Free)
Talk to Us First (Free) Fill out our intake form. We call you for a free consultation to understand your goals, current health status, and which protocol or combination makes sense for where you are. Whether you’re already a TRTPower patient or coming in for the first time, we meet you where you are.
Doctor Review & Prescription
Our doctor conducts a thorough medical evaluation, reviews your health history and existing labs, and prescribes the appropriate protocol. Some of our Longevity protocols—particularly Rapamycin—have specific candidacy criteria that require careful evaluation. We’ll be direct about what you qualify for and why. If additional bloodwork is needed, we coordinate it. Once approved, your prescription is prepared and shipped.
Ships to Your Door With Onging Support
Your medication arrives in discreet packaging with everything included—medication, supplies, and clear instructions. Injectable protocols come with step-by-step guidance and a care team available when you’re getting started. And that support doesn’t stop at delivery. Longevity medicine is not set-it-and-forget-it. Regular check-ins, lab monitoring to track biomarkers of aging, inflammation, and metabolic function, and protocol adjustments as your biology responds. We watch the numbers and adjust the plan—because the goal is measurable results, not just a monthly prescription.
What’s Included:
- Free consultation before you commit
- Comprehensive medical evaluation
- Doctor prescription if appropriate
- Discreet home delivery
- All supplies included (syringes, swabs for injection protocols)
- Professional guidance and clear instructions
- Regular monitoring and check-ins
- Provider support throughout treatment
NAD+ Injections: $149/month
Metformin: $49/month
Rapamycin: $199/month
Glutathione Injections: $99/month
Start Aging on Your Terms
The biology of aging is not fixed. The cellular systems behind how fast you decline—energy production, inflammation, metabolic function, cellular repair—are responsive to intervention. The question is whether you address them now, while the upside is high, or later, when you’re managing consequences instead of preventing them.
Talk to our care team. It’s free. We’ll look at where you are, what your goals are, and which protocols give you the most meaningful return—whether that’s one or all four.
No pressure. No guesswork. Just a straight conversation about the science, your options, and what’s actually right for you.
More Than Just Testosterone
TRT is our specialty, but we’re here for your complete health journey. Most men start with testosterone optimization—it’s the foundation. Once you’re dialed in and feeling like yourself again, we can help you build on that foundation with weight loss, performance optimization, sexual health, and longevity protocols. One crew, complete care.
